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Simultaneously, market leaders continue to improve and develop new treatments for these conditions

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Key Points The ubiquitinproteasome pathway promotes the degradation of proteins by first catalysing the formation of a polyubiquitin chain on the target protein

ScGrx7 and PfGrx both have typical ping-pong kinetics with GSSCys and GSH and cannot be saturated at infinite substrate concentrations in accordance with previous results from GSSEtOH assays on ScGrx7 (ref